Non-Hodgkins Lymphoma

Program Overview. At The Lacks Cancer Center at Saint Mary’s Health Care, our cancer treatment programs are increasing hope every day, thanks to a unique multidisciplinary model of care, which incorporates a staff of progressive physicians and the most innovative technologies available. In addition to this model, we continually review and apply the latest anti-cancer drugs, the newest staging and imaging techniques, such as PET scan technology, and the most effective surgical procedures to ensure the best outcomes in the treatment of non-Hodgkin’s lymphoma.

Lymphatic System Overview. The lymphatic system is the driving force behind the body’s immune system, filtering out unhealthy microorganisms and constantly fighting infection. The bone marrow, spleen, thymus gland and lymph nodes are among key tissues that play an active part in this system. Essentially, the bone marrow—tissue found within bones—produces white blood cells called lymphocytes, which travel to and reside in small pockets of tissue found throughout the body (lymph nodes). Lymphocytes are sent out by the lymph nodes to stalk unwanted bacteria and viruses in the blood. The lymphocytes then surround the unwanted organisms and release fluids that destroy them. They travel back to the lymph nodes, which filter out the newly destroyed “intruders.”

Non-Hodgkin’s Lymphoma Overview. Non-Hodgkin’s lymphoma is a cancer that originates in the lymphocytes (lymph cells), located primarily in the lymph nodes, organs of the lymphatic system and other lymphoid tissues. Non-Hodgkin’s lymphoma is typically distinguished from Hodgkin’s disease by studying the cells under a microscope. If Reed-Sternberg cells are present, non-Hodgkin’s disease can be ruled out.

Although non-Hodgkin’s can be categorized into three basic forms— indolent (slow-growing), aggressive (fast-growing) and highly aggressive—understanding the true classification of the disease can be a confusing prospect for patients. This is because there are over thirty types of the disease, as well as several different classification systems used in the diagnostic process. It is suggested that patients consult with a physician who specializes in this disease to understand the true nature of their diagnosis.

Risk Factors. Risk factors for adult non-Hodgkin lymphoma include the following:
 

• Being older, male and/or white
• A weakened immune system due to an inherited immune disorder or autoimmune disease
• A history of Helicobacter pylori infection
• Viruses such as, Human T-lymphotrophic virus type I, Epstein-Barr virus or HIV/AIDS
• Taking immunosuppressant drugs after an organ transplant
• Exposure to certain chemicals, such as pesticides, solvents or fertilizers

Signs and Symptoms. Please note that, although the following symptoms may be caused by adult non-Hodgkin lymphoma, there are other conditions that may display the same symptoms:
 

• Painless swelling in the lymph nodes of the neck, underarm, groin or stomach
• Constant fatigue
• Night sweats
• A skin rash or itchy, irritated skin
• Unexplained pain in the chest, abdomen or bones
• Unexplained fever, weight loss and poor appetite

To schedule a consult with our team of oncologists, simply ask your primary care physician for a referral or make a self-referral by calling 1-877-LACKS-MI or 616-685-LACK(S).